Best teaching strategies are necessary for making teaching smooth and effective. During the lesson design, an effective teacher selects a particular teaching strategy or set of strategies in order to make his/her teaching effective and create interest of students in learning. There are various teaching strategies for different teaching subjects. There are also strategies that are more specific for a particular subject area. This was a descriptive study which analyzed the impact on academic performance of grade 4 pupils after teaching them by using multimedia approach rather than conventional method of teaching science. The findings of the study shows that utilization of multimedia in teaching science and its impact to the academic performance of grade 4 pupils of Eulogio G. Cerrado Elementary School proved to be better than conventional method in teaching Science. The teaching by multimedia approach was effective therefore not a single student was found to be under extremely low level of achievement in Science so it is obvious that multimedia approach is an effective method in teaching Science. Implementing science lessons with use of multimedia may lead towards making a difference, which produce in pupils a long-term memories about the concept.