The major problem of the study is to assess the extent of implementation of human resource practices and their effects on employees’ motivation. This study made use of descriptive correlational design to provide information on variables. The data were gathered from a total of 179 public secondary high school teachers through a standardized questionnaire. The data gathered were regressed via SPSS. Findings revealed that human resource practices namely initial screening, manpower planning, job design, training and development, quality circle and pay system have been implemented to a great extent and that, pay system and training and development were the strong predictors of employees’ motivation. The study can offer support so organizations can have a superior perception of the significance of motivating employees through effective, more functional, and innovative human resource practices processes in the organization.